A man in a wheelchair crosses the path of a family in a van, causing the driver to lose control of the vehicle.  The ensuing wreck results in the deaths of a woman and her daughter, the surviving husband/father bent on a path of revenge toward men in wheelchairs, launching him into a lust for murder. Bill Colón, diagnosed with multiple sclerosis and forced to use a wheelchair on occasion, attends a support group whose members are falling prey to the crazed serial killer. His brother-in-law, Luis Ortiz is the homicide detective assigned to the case.
 In time, Luis and Bill realize that Bill, too, is a target and must take action to bring this killing spree to an end. The killer, his intended victim and a pair of brothers whose lives have traveled in opposite directions, all converge in a desolate warehouse to confront each other.
 Feel the hatred of a cold-blooded killer and the fear in his victims, who have already been relegated to a life of loss.

Chronic Nights